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KMID : 0365220160530020009
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Korean Journal of Public Health
2016 Volume.53 No. 2 p.9 ~ p.18
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Health Hazard and Odor Threshold of Chemicals
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Yoon Chung-Sik
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Abstract
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Results: Among the 656 chemicals having Korean OELs, 123 chemicals had odor threshold values. There were no correlation (R2=0.0036) between 8-hour Time Weighted Average(TWA) and odor threshold values in 112 chemicals which had both 8-hour TWA and odor threshold values. This fact means that health hazard could not be judged by sense of smell in the workplace or other environment. The classification of the chemicals having odor threshold values into three categories, the ones which had higher odor threshold values than OELs, the ones had lower odor threshold values than OELs and the ones having similar values, could be used to manage chemicals at the workplace. Three chemicals like decaborane(0.05ppm), formaldehyde(0.5ppm), and hydrogen fluoride(0.5ppm) had the same value of 8hr-TWA and odor threshold values. The correlations of odor threshold with vapor pressure (R2=0.0024), with LD50(R2=0.0043), and with LC50(R2=0.0025), were weak. Though it is very difficult to elucidate the relationship between odor threshold and chemical structure or its reactive group, this study showed several structural similarities and reactive groups for chemicals having very low odor threshold values.
Conclusion: This study found that there were no correlation between odor thresholds and health hazards using index such as OELs(R2=0.06), LD50 (R2=0.004) and LC50(R2=0.003). There was moderate correlation between OELs (R2=0.16) and LD50(R2=0.38), between OELs and LC50(R2=0.14).
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KEYWORD
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odor, threshold, chemicals, occupation, exposure limit, Lethal dose, Lethal concentration, TWA
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